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Sermorelin is a synthetic analog composed of a sequence of 29 amino acids representing the 1-29 fragment of GHRH. The Sermorelin hormone has long been used in clinics as an anti-aging treatment. This is why it is not well known in the world of bodybuilding. But this does not mean that it’s ineffective, and it is increasingly used by some bodybuilders.

Its one major flaw is its very short life of about 10 minutes. Its other main disadvantage is that it does not bind well to the pituitary receptor. Additionally, it’s quickly decomposed by enzymes in the blood. This is why other GHRH peptides are preferred.

Sermorelin in Bodybuilding

However there are many reasons to appreciate Sermorelin, especially in bodybuilding. It helps increase lean body mass and reduce fat. It also improves sleep and recovery after exercise. It improves resistance and strengthens the heart. Among other things, it increases IGF-1 production and lastly, it boosts the immune system. It is capable of increasing protein synthesis, preserving and enhancing all of the body’s internal organs except the brain, and also increasing the liver’s glycogenesis. Despite the fact that Sermorelin’s life is very short, the number of factors it improves make it almost indispensable. It’s a highly used peptide in some clinics and is often referred to as the major anti-aging peptide. It can firmly reverse some effects of aging in adults. One of Sermorelin’s other benefits is that it is much more affordable. It is 50-60% less expensive than another HGH. Additionally, it is legally prescribed by doctors.

Sermorelin’s Effects


Positives of Sermorelin

  • Increases lean muscle mass
  • Increases bone density
  • Reduces body fat
  • Strengthens the heart
  • Strengthens immune system
  • Stimulates the pituitary gland
  • Anti-age


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Negatives of Sermorelin

  • Overly short life (10 minutes)
  • Injections just before workouts
  • Redness in the face
  • Injections before going to bed


Sermorelin Peptide Advice and Usage

It’s advised to take Sermoreline for at least three months but not more than six months past the initial intake. It’s a delicate powder that should be stored away from light in a dry and cool place. It should be reconstituted with injectable sodium chloride or even with bacteriostatic or sterilized water. Take Sermorelin with subcutaneous injections, typically in the stomach area.

→Sermorelin Dosage

Normally, 300mcg of Sermorelin should be taken one hour just before bedtime. But it is also possible to take injections one hour before training sessions at a dose of 200-300mcg.

The dose of Sermorelin can go up to 600mcg/day.

Like any GHRH it can be associated with a GHRP or Ipamorelin to maximize the release of growth hormones.


Sermorelin Dosage Information

The typical range of Sermorelin dosage is between 200 mcg to 1000 mcg. It is used for various purposes such as Anti-aging, weight loss, recovery, and bodybuilding. Here we will discuss the best-recommended dosage of Sermorelin.

→ Sermorelin Dosage For Weight Loss | Anti-Aging

When you follow the below-recommended dose, you will get effective results in terms of weight loss and anti-aging purposes:

  • You can take 200 mcg to 400 mcg per day.
  • The ideal cycle is 3 to 6 months

→ Sermorelin Dosage For Bodybuilding

When users use Sermorelin for bodybuilding purposes, they take slightly higher doses to get effective results.

  • You can take 400 mcg to 500 mcg per day.
  • The ideal cycle is 3 to 6 months

Note that high dose and long-term use of Sermorelin may cause various side effects. So before taking high doses, take advice from the professional coaching experts. The off-Sermorelin cycle is for one month, but some users can also perform it for up to 6 months.

→ Sermorelin Dosage For Recovery

Sermorelin lower doses are also effective to get recover from various injuries. You can use:

  • 100 mcg to 200 mcg per day.
  • The ideal cycle is for 3 to 6 months

You can change the doses between the cycles; this will help you to maintain your hormone level. You can use the off-cycle for 3 to 6 months.



Sermorelin Post-Cycle Therapy

When users artificially manipulate the testosterone levels, the body’s other functions may stop operating the testosterone production, or they can completely shut down the testosterone production because of the high level of exogenous hormone. To overcome this, you should perform post-cycle therapy.
Post-cycle therapy reactivates your body with:

  • Follicle-Stimulating Hormone (FSH): It stimulates sperm production in testes.
  • Luteinizing Hormone (LH): It stimulates testosterone production in the testes.

In addition, the PCT also helps you get rid of various side effects such as loss of libido, lower energy level, loss of muscle mass, and many more.



Sermorelin is a synthetic variation of Growth Hormone (GH), the endogenous hormone is responsible for stimulating natural growth hormone production. It works by binding the GH-releasing hormone receptor to the pituitary gland. Sermorelin is a peptide hormone that naturally promotes the production and secretion of growth hormones. It provides the natural production of human growth hormone when you consume the correct dose of it.

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